Chacruna started producing large-scale conferences in Mexico in 2015, and then yearly spring conferences in the West Coast since 2018. Psychedelic Culture 2025 will continue our tradition of exploring cutting-edge themes that are largely absent from the mainstream psychedelic conversation. Chacruna’s interdisciplinary conferences are well known for bringing diverse voices together, combining intellectual vision and rigor, community, activism, heart and soul. In the midst of the so called psychedelic renaissance, it is more important than ever to promote dialogues between scientists and communities who have been truly involved with these medicines, to have knowledge about the proper ways to use and steward them.